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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXD4 All Species: 2.73
Human Site: S352 Identified Species: 6
UniProt: Q12950 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12950 NP_997188.2 439 47251 S352 R G A T A P C S S D R Q A C R
Chimpanzee Pan troglodytes NP_001009014 413 45421 V325 A S L S A L R V L C K G S G E
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q60688 444 48029 L357 L L Q H P P C L L H P Q A A S
Rat Rattus norvegicus Q63245 101 11924 P20 T M A I L Q S P Q K K L T L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516678 728 77542 S499 A P S L L H V S A A A A A A R
Chicken Gallus gallus P79772 394 40977 K310 G A A G S I V K S E P S S R P
Frog Xenopus laevis Q9DEN4 371 40000 E290 A A S I I K S E P S S R P S F
Zebra Danio Brachydanio rerio NP_571365 371 40457 E290 T A S I I K S E P S S R P S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02361 456 49036 E358 T E A D A E A E G D D D S C E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496411 333 37274 P252 L P Q G M P F P P R M M H P M
Sea Urchin Strong. purpuratus XP_001188749 401 43606 S317 I D S L L N G S T A P P S T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 N.A. N.A. N.A. 48.6 20.5 N.A. 33 38.2 34.8 32.7 N.A. 30.9 N.A. 31.2 34.8
Protein Similarity: 100 83.1 N.A. N.A. N.A. 55.6 21.6 N.A. 41.4 46.7 46.4 45.3 N.A. 44 N.A. 43.2 44.8
P-Site Identity: 100 6.6 N.A. N.A. N.A. 26.6 6.6 N.A. 20 13.3 0 0 N.A. 26.6 N.A. 6.6 6.6
P-Site Similarity: 100 26.6 N.A. N.A. N.A. 26.6 13.3 N.A. 33.3 33.3 13.3 13.3 N.A. 33.3 N.A. 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 28 37 0 28 0 10 0 10 19 10 10 28 19 0 % A
% Cys: 0 0 0 0 0 0 19 0 0 10 0 0 0 19 0 % C
% Asp: 0 10 0 10 0 0 0 0 0 19 10 10 0 0 0 % D
% Glu: 0 10 0 0 0 10 0 28 0 10 0 0 0 0 19 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 19 % F
% Gly: 10 10 0 19 0 0 10 0 10 0 0 10 0 10 0 % G
% His: 0 0 0 10 0 10 0 0 0 10 0 0 10 0 0 % H
% Ile: 10 0 0 28 19 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 19 0 10 0 10 19 0 0 0 0 % K
% Leu: 19 10 10 19 28 10 0 10 19 0 0 10 0 10 0 % L
% Met: 0 10 0 0 10 0 0 0 0 0 10 10 0 0 10 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 19 0 0 10 28 0 19 28 0 28 10 19 10 10 % P
% Gln: 0 0 19 0 0 10 0 0 10 0 0 19 0 0 0 % Q
% Arg: 10 0 0 0 0 0 10 0 0 10 10 19 0 10 19 % R
% Ser: 0 10 37 10 10 0 28 28 19 19 19 10 37 19 19 % S
% Thr: 28 0 0 10 0 0 0 0 10 0 0 0 10 10 10 % T
% Val: 0 0 0 0 0 0 19 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _